 |
 |
Presentation
The Centre for the Study of Liver Disease (CSF) is a structure which unites a molecular based research activity with a clinical activities of the Clinical Liver Unit. This type of alliance which is infrequent though not unique in the Italian hepatological reality, allows the identification within the CSF of an operational example of molecular medicine, in this case, hepatological medicine.
Personnel:
12 peopleField of interest and technologies
The Centre displays expertise in the field
of advanced technologies for the study of physiological and pathological
aspects of the liver. In particular, the thrust of the CSF is into the study
of molecular transport mechanisms of various organic anions (bilirubin and
MRI contrast agents) and of bilirubin cellular damage mechanisms at cerebral
and placental levels.
Associated with this research activity, the Centre carries out investigations
into the molecular pathology of certain liver diseases, amongst which are
hepatic carcinoma and the congenital syndromes with non-conjugated hyperbilirubinemia.
Products, services and applications
The Centre for Liver Studies is active in a number of research directions:
- study of hepatic transport molecular mechanisms of bilirubin and other organic compounds related to the physiopathology of jaundice;
- study of neurological damage caused by bilirubin;
- study of the expression of different proteins correlated with hepatic pathologies implicated in pharmaceutical transport;
- early molecular diagnosis of primary carcinoma of the liver.
The CSF also carries out intense training activities by means of study bursaries
and scholarships and specific specialisation programmes at the national,
European and international levels.
The management of the CSF is entrusted to an especially constituted technical
scientific committee.
The administrative management is carried out by a mixed public-private company
with an autonomous board whose characteristics must mirror the parties making
up the mixed company.
CSF scientific collaboration
As evidenced by the projects, the CSF interacts scientifically with the national and international scientific and clinical bodies:
- Bracco Imaging SpA
- AOTS n. 1 Triestina
- University of Trieste
- IRCCS Burlo Garofalo
- IRCCS CRO, Aviano
- University of Udine
- University of Naples
- University of Messina
- IRCS Oasi Troina, Enna
- National University of Rosario (Argentina)
- University of Graz (Austria)
- University of Lyon (France)
- Ejikman Institute, Jakarta (Indonesia)
- University of Malaya (Malesia)
- Medical Clinic of sur (Mexico)
- University of Amsterdam (Netherlands)
- University of Groningen (Netherlands)
- University of Lisbon (Portugal)
- University of Lubiana (Slovenia)
- University of Leon (Spain)
- University of Barcelona (Spain)
- University of Budapest (Hungary)
- University of Washington, Seattle, WA (USA)
- Commonwealth Medical Institute, Richmond, VA (USA)
- University of Michigan, Ann Arbor, MI (USA)
- Jackson Institute, Maine (USA)
- University of Thay Nieng (Vietnam)