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Projects
- Expression of Ape1/Ref1 in chronic liver diseases and its role in primary liver carcinoma. Study of the cellular mechanisms and of the oxidative stress involved in chronic liver diseases and mechanisms with particular attention being given to the expression of Ape1/Ref1.
- Multiple biopsy project: study of the epidemiological profile of chronic liver diseases, of primary liver carcinoma and of histological-molecular models which could be the basis of these pathologies.
- Study of Hypobetalipoproteinemia in steatosic patients: Study of the role of familial hypobeta-lipoproteinemia (FHBL) in hepatic steatosis in families with this gene mutation (Study in collaboration with the University of Modena).
- HLA study in patients affected by primary biliary cirrhosis (Multicentre study). Multicentric study of the distribution amongst the principal geographic Italian areas of the HLA-DRB1*11 and HLA-DRB1*08 alleles to obtain answers about the possible role of the HLA genes in progression of the disease.
- FIST: Genomics and proteomics of the normal and pathologic liver: identification of the genes involved in the cellular cycle, in metabolic control and in membrane transporters in subjects with viral hepatic infections.
- HCC diagnosis and surveillance: Study of chronic liver diseases and modes of radiological and heamatological follow up for early diagnosis of hepatocarcinoma.
- Project Dionysos Follow-up: Natural history and complications of liver diseases at Cormons (GO) and Campogalliano(MO).