Genome Engineering & Biotechnology Unit

Group Leader:
Gianluca Petris

Francesca Agostini (Postdoc Researcher)
Miriam Saponaro (Postdoc Researcher)

Research Description:

Development and application of chromosome transfer / chromosome elimination technologies in human cells, to study large-scale genome alterations and enable new cell engineering strategies.

• Functional and mechanistic studies on extrachromosomal DNA (ecDNA) maintenance and its vulnerability to replication stress.